Melanocyte-keratinocyte transplantation procedure: A few insights
نویسندگان
چکیده
منابع مشابه
Epidermal Healing in Burns: Autologous Keratinocyte Transplantation as a Standard Procedure: Update and Perspective
BACKGROUND Treatment of burned patients is a tricky clinical problem not only because of the extent of the physiologic abnormalities but also because of the limited area of normal skin available. METHODS Literature indexed in the National Center (PubMed) has been reviewed using combinations of key words (burns, children, skin graft, tissue engineering, and keratinocyte grafts). Articles inves...
متن کاملMelanocyte-keratinocyte interactions in vivo: the fate of melanosomes.
Studies on pigment donation in tissue culture (1-5) indicate that melanosome transfer is a cytophagic process during which a portion of a melanocyte dendrite is pinched off by the epidermal cell so that melanosomes and melanocyte cytoplasm are incorporated into the keratinocyte. At the ultrastructural level, one would ex-rect to see, at this stage, a cluster of melanosomes embedded in a cytopla...
متن کاملLong-term follow-up study of segmental and focal vitiligo treated by autologous, noncultured melanocyte-keratinocyte cell transplantation.
OBJECTIVE To evaluate long-term efficacy and safety of melanocyte-keratinocyte cell transplantation in the management of segmental and focal vitiligo. DESIGN A simpler and modified method based on that of Olsson and Juhlin was performed. This method uses a shaved biopsy skin sample up to one tenth the size of the recipient area. The skin sample is incubated, and the cells are mechanically sep...
متن کاملNon-cultured melanocyte/keratinocyte transplantation for the treatment of stable vitiligo on the face: report of two cases*
There are many alternatives to treat vitiligo, including surgical procedures, which are recommended for patients resistant to other therapies. The melanocyte/keratinocyte transplantation consists in the separation of epidermal cells obtained from a donor site and spreading these cells on the depigmented and dermabraded recipient area. Two patients were submitted to transplantation, showing more...
متن کاملEvaluation of treatment response to autologous transplantation of noncultured melanocyte/keratinocyte cell suspension in patients with stable vitiligo*
BACKGROUND Vitiligo is a chronic disease characterized by the appearance of achromic macules caused by melanocyte destruction. Surgical treatments with melanocyte transplantation can be used for stable vitiligo cases. OBJECTIVES To evaluate treatment response to the autologous transplantation of noncultured epidermal cell suspension in patients with stable vitiligo. METHODS Case series stud...
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ژورنال
عنوان ژورنال: Indian Journal of Dermatology, Venereology, and Leprology
سال: 2016
ISSN: 0378-6323
DOI: 10.4103/0378-6323.172904